Cats have some neurological symptoms, which are mostly caused by the disease, and many infectious diseases will have corresponding neurological symptoms in the later stage. Of course, this is a manifestation of serious neurological symptoms. Sometim...
Cats have some neurological symptoms, which are mostly caused by the disease, and many infectious diseases will have corresponding neurological symptoms in the later stage. Of course, this is a manifestation of serious neurological symptoms. Sometimes cats will also experience sudden manic symptoms due to psychological depression, estrus, etc. At this time, in order to avoid greater harm, the cat needs to be calmed down.
In some ways, music has a relaxing effect on a cat and can reduce its aggressive behavior. So, you can play your music with gentle background music, which also has the effect of soothing the cat. If it is a lonely old cat, you might as well add a kitten to it. Because one old and one young are more likely to accept each other, but it should be noted that the kitten should be taken home by someone an old cat never knows. This person appears in the hope that the old cat will not associate you with the kitten and become jealous.
In addition, when a cat feels nervous, it will naturally attack its enemies with its claws, so you should cut the cat's nails frequently. When cutting, it is best to hold it with another person to attract its attention. Selection of sedatives
1, alpha2 adrenergic antagonist
alpha2 antagonist is used to reverse the sedation and cardiovascular effects of alpha2 agonists. Currently, there are three antagonists: toprazoline, yohimbine, and atemec. If antagonist is given a relatively excessive dose, side effects related to neurological (excitation and muscle tremor), cardiovascular (hypotension and tachycardia), and gastrointestinal (salivation and diarrhea) can occur. Under Rapid IV, deaths were also reported. Its mechanism may be a rapid reversal of vasoconstriction, which for the sympathetic nervous system, does not have enough time to increase CO, causing severe hypotension.
2. Most pharmacological effects of benzodiazepine sedatives
benzodiazepines are accomplished by regulating GABA-mediated nerve conduction. In the central neuronal membranes of mammals, GABA is the main inhibitory neurotransmitter. These receptors are also found in the autonomic ganglion outside the central nervous system. In neural conduction, two types of GABA receptors are involved: the GABAA receptor complex is a ligand-gated chloride channel with five glycoprotein subunits around the central pore. The benzodiazepine binding site, which is also the binding site of other injected anesthetics (barbital salt, propofol, etomidate), is located in the GABAA receptor complex. Benzodiazepines enhance the binding of GABA and GABAA receptors, increasing the frequency of channel opening. However, barbital salt enhances intrinsic activity and increases the duration of channel opening. Both mechanisms increase the conduction of chloride ions and hyperpolarization of cell membranes, reducing neuronal excitability. In the absence of GABA, benzodiazepines have no intrinsic agonist activity and cannot alter the conduction of chloride ions. This intrinsic activity deletion of central nervous system activity (i.e., it does not inhibit the excitability of CNS), makes the safe range of benzodiazepines more wide than that of barbiturate. There are three types of ligands bound to benzodiazepine receptors: agonists, reversal agonists, and antagonists. The agonist binds to benzodiazepine receptors and produces sedation, anti-anxiety, muscle relaxation and anti-spasm in most animals. Reversal agonists bind to the same receptor, resulting in opposite effects. Antagonists have a high affinity with benzodiazepine receptors and have little or no intrinsic activity. Antagonists block or reverse the effects of agonists and reverse the agonists and reverse the effects of agonists. Diazepam, midazolam, and zolazepam are all commonly used benzodiazepine agonists in veterinary clinics. Diazepam and midazolam are mainly used as sedatives, muscle relaxants, and anti-spasmodic drugs. Zolazepam can be combined with isolated anesthetics (tiedatamine), and is a product approved for cat anesthetics in the United States.
